HBXIP anticorps (AA 41-91) (HRP)

N° du produit ABIN900211

Cet anticorps Lapin Polyclonal détecte spécifiquement HBXIP dans ELISA, IHC (fro) et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour HBXIP anticorps (AA 41-91) (HRP) (ABIN900211)

Antigène: HBXIP (Hepatitis B Virus X-Interacting Protein (HBXIP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HBXIP est conjugé à/à la HRP

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-HBXIP anticorps (HRP)

Épitope: AA 41-91

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HBXIP

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur HBXIP

Antigène: HBXIP (Hepatitis B Virus X-Interacting Protein (HBXIP))

Autre désignation: HBXIP

Classe de substances: Viral Protein

Sujet:

Synonyms: HBV X interacting protein, HBX interacting protein, Hepatitis B virus X interacting protein, MGC71071, XIP, HBXIP_HUMAN.

Background: HBXIP (Hepatitis B virus X interacting protein) complexes with the C-terminus of hepatitis B virus X protein (HBx) and down-regulates hepatitis B virus (HBV) replication. When complexed to BIRC5, it interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway.

ID gène: 10542

Pathways: Signalisation PI3K-Akt, Regulation of Cell Size