Myosin VIIA anticorps (AA 851-950) (Biotin)

N° du produit ABIN907515

Cet anticorps anti-Myosin VIIA est un anticorps Lapin Polyclonal détectant Myosin VIIA dans ELISA, IHC (fro) et IHC (p). Adapté pour Humain et Souris.

Aperçu rapide pour Myosin VIIA anticorps (AA 851-950) (Biotin) (ABIN907515)

Antigène: Myosin VIIA (MYO7A)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Myosin VIIA est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Myosin VIIA anticorps (Biotin)

Épitope: AA 851-950

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Myosin VIIa

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Myosin VIIA

Antigène: Myosin VIIA (MYO7A)

Autre désignation: Myosin 7a

Sujet:

Synonyms: DFNB2, MYU7A, NSRD2, USH1B, DFNA11, MYOVIIA, Unconventional myosin-VIIa, MYO7A

Background: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. In the retina, plays an important role in the renewal of the outer photoreceptor disks. Plays an important role in the distribution and migration of retinal pigment epithelial (RPE) melanosomes and phagosomes, and in the regulation of opsin transport in retinal photoreceptors. In the inner ear, plays an important role in differentiation, morphogenesis and organization of cochlear hair cell bundles. Involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity (By similarity). Motor protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.

ID gène: 4647

UniProt: Q13402

Pathways: Sensory Perception of Sound