NOC2L anticorps (AA 251-350) (Cy5)

N° du produit ABIN908587

Cet anticorps Lapin Polyclonal détecte spécifiquement NOC2L dans IF (cc) et IF (p). Il présente une réactivité envers Humain.

Aperçu rapide pour NOC2L anticorps (AA 251-350) (Cy5) (ABIN908587)

Antigène: NOC2L (Nucleolar Complex Associated 2 Homolog (NOC2L))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOC2L est conjugé à/à la Cy5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-NOC2L anticorps (Cy5)

Épitope: AA 251-350

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human NOC2L

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur NOC2L

Antigène: NOC2L (Nucleolar Complex Associated 2 Homolog (NOC2L))

Autre désignation: NOC2L

Sujet:

Synonyms: NIR, NOC2 like, Novel INHAT inhibitor of histone acetyltransferase repressor, Nucleolar complex associated 2 homolog S. cerevisiae, Protein NOC2 homolog, NOC2L_HUMAN.

Background: NOC2L is a transcriptional corepressor with inhibitor of histone acetyltransferase (INHAT) activity. NOC2L or NIR (Novel INHAT Repressor) is ubiquitously expressed throughout embryonic development and adulthood. It is a potent transcriptional corepressor that is not blocked by histone deacetylase inhibitors and is capable of silencing both basal and activator-driven transcription. NOC2L directly binds to nucleosomes and core histones and prevents acetylation by histone acetyltransferases, thus acting as a bona fide INHAT.

ID gène: 26155

Pathways: Negative Regulation of intrinsic apoptotic Signaling