PAX8 anticorps (AbBy Fluor® 555)

N° du produit ABIN910189

Cet anticorps Lapin Polyclonal détecte spécifiquement PAX8 dans WB, IF (cc) et IF (p). Il présente une réactivité envers Humain, Souris, Rat, Chien et Boeuf (Vache).

Aperçu rapide pour PAX8 anticorps (AbBy Fluor® 555) (ABIN910189)

Antigène: PAX8 (Paired Box 8 (PAX8))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAX8 est conjugé à/à la AbBy Fluor® 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-PAX8 anticorps (AbBy Fluor® 555)

Réactivité croisée: Boeuf (Vache), Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from mouse PAX8

Isotype: IgG

Information d'application

Indications d'application: FCM(1:100-500)
IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PAX8

Antigène: PAX8 (Paired Box 8 (PAX8))

Autre désignation: PAX8

Sujet:

Synonyms: Paired Box Gene 8, paired box homeotic gene 8, Paired box protein Pax 8, Paired Domain Gene 8, PAX 8,PAX-8,

Background: This protein is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain, an octapeptide, and a paired-type homeodomain. This family plays critical roles during fetal development and cancer growth. The specific function of the PAX8 is unknown but it may involve kidney cell differentiation, thyroid development, or thyroid dysgenesis. Alternative splicing in the gene by inclusion or exclusion of exons 7 and/or 8 has produced several known products but the biological significance of the variants is unknown. Several other splice variants have been proposed but the full nature of these products has not been described. Pax8 is also a marker of otic progenitor cells.

Poids moléculaire: 50kDa

ID gène: 18510

Pathways: Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation