PCDHB11 anticorps (AA 141-240) (AbBy Fluor® 488)

N° du produit ABIN910251

Cet anticorps anti-PCDHB11 est un anticorps Lapin Polyclonal détectant PCDHB11 dans WB, IF (cc) et IF (p). Adapté pour Humain.

Aperçu rapide pour PCDHB11 anticorps (AA 141-240) (AbBy Fluor® 488) (ABIN910251)

Antigène: PCDHB11 (Protocadherin beta 11 (PCDHB11))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDHB11 est conjugé à/à la AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-PCDHB11 anticorps (AbBy Fluor® 488)

Épitope: AA 141-240

Homologie: Human,Mouse,Rat,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PCDHB11

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PCDHB11

Antigène: PCDHB11 (Protocadherin beta 11 (PCDHB11))

Autre désignation: PCDHB11

Sujet:

Synonyms: MGC138337, Cadherin ME2, ME2, MGC138337, MGC142171, MGC142171, PCDBB_HUMAN, PCDH beta 11, PCDH BETA11, PCDH-beta-11, PCDHB11, Protocadherin beta 11, Protocadherin beta-11.

Background: PCDHB11 is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. PCDHB11 clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

ID gène: 56125