PGC anticorps (AA 21-120) (AbBy Fluor® 555)

N° du produit ABIN910826

L’anticorps Lapin Polyclonal anti-PGC a été validé pour IF (cc) et IF (p). Il convient pour détecter PGC dans des échantillons de Humain.

Aperçu rapide pour PGC anticorps (AA 21-120) (AbBy Fluor® 555) (ABIN910826)

Antigène: PGC (Pepsinogen C (PGC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PGC est conjugé à/à la AbBy Fluor® 555

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-PGC anticorps (AbBy Fluor® 555)

Épitope: AA 21-120

Réactivité croisée: Humain

Homologie: Mouse,Rat,Cow,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PG-C

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PGC

Antigène: PGC (Pepsinogen C (PGC))

Autre désignation: Pg-C/Pepsinogen 2

Sujet:

Synonyms: PEPC, PGII, Gastricsin, Pepsinogen C, PGC

Background: This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq].

ID gène: 5225

UniProt: P20142