CD248 anticorps (AA 251-350) (AbBy Fluor® 647)

N° du produit ABIN917320

Cet anticorps Lapin Polyclonal détecte spécifiquement CD248 dans WB, FACS, IF (cc) et IF (p). Il présente une réactivité envers Humain et Souris et a été mentionné dans 2+ publications.

Aperçu rapide pour CD248 anticorps (AA 251-350) (AbBy Fluor® 647) (ABIN917320)

Antigène: CD248 (CD248 Molecule, Endosialin (CD248))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD248 est conjugé à/à la AbBy Fluor® 647

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-CD248 anticorps (AbBy Fluor® 647)

Épitope: AA 251-350

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TEM 1

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-CD248 (AbBy Fluor® 647) (ABIN917320)

Farinon, Clarimundo, Pedrazza, Gulko, Zuanazzi, Xavier, de Oliveira: "Disease modifying anti-rheumatic activity of the alkaloid montanine on experimental arthritis and fibroblast-like synoviocytes." dans: European journal of pharmacology, Vol. 799, pp. 180-187, (2017) (PubMed).

Clarimundo, Farinon, Pedó, Teixeira, Nör, Gulko, Xavier, de Oliveira: "Gastrin-releasing peptide and its receptor increase arthritis fibroblast-like synoviocytes invasiveness through activating the PI3K/AKT pathway." dans: Peptides, Vol. 95, pp. 57-61, (2017) (PubMed).

Détails sur CD248

Antigène: CD248 (CD248 Molecule, Endosialin (CD248))

Autre désignation: Tem1/Cd248

Sujet:

Synonyms: TEM1, CD164L1, Endosialin, Tumor endothelial marker 1, CD248

Background: The transmembrane glycoprotein Tumor endothelial marker 1 (TEM1) is highly expressed in tumor endothelial cells however it is barely detectable on normal endothelial cells. It is believed to play a role in tumor angiogenesis. It is expressed in stromal fibroblasts, metastatic hepatic lesions and during angiogenesis of corpus luteum formation and wound healing. TEM1 is being investigated as a potential target for cancer treatment.

ID gène: 57124

UniProt: Q9HCU0