TLR11 anticorps (Internal Region)
Aperçu rapide pour TLR11 anticorps (Internal Region) (ABIN920631)
Antigène
Voir toutes TLR11 (Tlr11) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Attributs du produit
- Positive Control: RAW26.7 cell lysate. Located in membrane.
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Purification
- Antigen Immunoaffinity purified
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Immunogène
- Rabbit polyclonal TLR11 antibody was raised against a peptide corresponding to 16 amino acids near the middle of mouse TLR11.
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Isotype
- IgG
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Indications d'application
- Western blot: use at 0.5-2 µg/mL
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Restrictions
- For Research Use only
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Buffer
- Phosphate buffered saline with 0.02% sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- TLR11 (Tlr11) (Toll-Like Receptor 11 (Tlr11))
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Sujet
- Toll-like receptors (TRLs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TRL11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacterial, and mice lacking TLR11 showed a much greater susceptibility to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system. Synonyms:
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Poids moléculaire
- 106 kDa
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Pathways
- Activation of Innate immune Response
Antigène
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