4-Hydroxy-2-Hexenal (4-HHE) anticorps

N° du produit ABIN920668

Cet anticorps Souris Monoclonal détecte spécifiquement 4-Hydroxy-2-Hexenal (4-HHE) dans IHC.

Aperçu rapide pour 4-Hydroxy-2-Hexenal (4-HHE) anticorps (ABIN920668)

Antigène: 4-Hydroxy-2-Hexenal (4-HHE)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Immunohistochemistry (IHC)

Clone: HHE53

Détail du produit

Specificité: Specific for HHE-modified protein (especially HHE-His Michael adduct)

Purification: Protein A purified.

Immunogène: HHE-modified keyhole-lympet hemocyanine.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Immunohistochemistry: Recommended antibody concentration is 0.5 - 1.0 µg/mL on paraformaldehyde fixed tissue.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Monoclonal antibody at 100 µg/mL in 10 mM PBS containing 0.1 % NaN3 and protein stabilizer. Prepared as ascite.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détail du antigène

Antigène: 4-Hydroxy-2-Hexenal (4-HHE)

Classe de substances: Chemical

Sujet: 4-hydroxy-2-alkenal is one of the major lipid peroxidation products, and shows many biological effects such as high toxicity to cells. Among them, 4-hydroxy-2-hexenal (HHE) is an aldehyde formed during peroxidation of n-3 fatty acids such as docosahexaenoic acid. HHE is a highly reactive aldehyde and reacts with histidine residue of protein to form Michael- addition type adducts. This antibody is specific for HHE-histidine Michael adduct (HHE-His) and enables detection of HHE-His in tissue samples.