TIAL1 anticorps (C-Term)

N° du produit ABIN925990

Détail du produit anti-TIAL1 anticorps

Antigène: TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Poulet, Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIAL1 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Chien, Souris, Rat (Rattus), Poulet, Grenouille, Poisson zebré (Brachydanio rerio)

Immunogène: TIAL1 antibody was raised in rabbit using the C terminal of TIAL1 as the immunogen

Information d'application

Indications d'application: WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

TIAL1 Blocking Peptide, catalog no. 33R-9984, is also available for use as a blocking control in assays to test for specificity of this TIAL1 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur TIAL1

Antigène: TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))

Autre désignation: TIAL1 (TIAL1 Produits)

Synonymes: anticorps TCBP, anticorps TIAR, anticorps 5330433G13Rik, anticorps AL033329, anticorps mTIAR, anticorps zgc:66130, anticorps tcbp, anticorps tiar, anticorps TIA1 cytotoxic granule associated RNA binding protein like 1, anticorps Tia1 cytotoxic granule-associated RNA binding protein-like 1, anticorps TIA1 cytotoxic granule-associated RNA binding protein-like 1, anticorps TIAL1, anticorps Tial1, anticorps tial1

Sujet: The protein encoded by TIAL1 is a member of a family of RNA-binding proteins and possesses nucleolytic activity against cytotoxic lymphocyte target cells. The gene product is a cytotoxic granule-associated protein and has been shown to bind specifically to poly(A) homopolymers and to fragment DNA in permeabilized target cells. It has been suggested that members of this protein family may be involved in the induction of apoptosis. One isoform contains a lysosome-targeting motif in its C-terminal auxiliary domain, however, alternative splicing results in a T-cluster DNA-binding isoform, differing at the C-terminus where a hydrophobic sequence replaces the lysosome-targeting motif. Synonyms: Polyclonal TIAL1 antibody, Anti-TIAL1 antibody, TIA1 cytotoxic granule-associated RNA binding protein-like 1 antibody.