KPNB1 anticorps (N-Term)

N° du produit ABIN926686

Cet anticorps Lapin Polyclonal détecte spécifiquement KPNB1 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour KPNB1 anticorps (N-Term) (ABIN926686)

Antigène: KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KPNB1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KPNB1 anticorps

Épitope: N-Term

Purification: Purified

Immunogène: KPNB1 antibody was raised in rabbit using the N terminal of KPNB1 as the immunogen

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Commentaires:

KPNB1 Blocking Peptide, (ABIN937840), is also available for use as a blocking control in assays to test for specificity of this KPNB1 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur KPNB1

Antigène: KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))

Autre désignation: KPNB1

Sujet: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. Synonyms: Polyclonal KPNB1 antibody, Anti-KPNB1 antibody, karyopherin, importin beta 1 antibody, IMB1 antibody, IPO1 antibody, IPOB antibody, Impnb antibody, MGC2155 antibody, MGC2156 antibody, MGC2157 antibody, NTF97 antibody.

Pathways: Protein targeting to Nucleus