SIRPA anticorps (C-Term)

N° du produit ABIN926850

Détail du produit anti-SIRPA anticorps

Antigène: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIRPA est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Souris, Rat (Rattus), Boeuf (Vache), Porc

Purification: Purified

Immunogène: SIRPA antibody was raised in rabbit using the C terminal of SIRPA as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

SIRPA Blocking Peptide, catalog no. 33R-7762, is also available for use as a blocking control in assays to test for specificity of this SIRPA antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur SIRPA

Antigène: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Autre désignation: SIRPA (SIRPA Produits)

Sujet: SIRPA is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. Synonyms: Polyclonal SIRPA antibody, Anti-SIRPA antibody, signal-regulatory protein alpha antibody, BIT antibody, CD172A antibody, MFR antibody, MYD-1 antibody, P84 antibody, PTPNS1 antibody, SHPS-1 antibody, SHPS1 antibody, SIRP antibody, SIRP-ALPHA-1 antibody, SIRPalpha antibody, SIRPalpha2 antibody.