CCR5 anticorps (Middle Region)

N° du produit ABIN927305

L’anticorps anti-CCR5 Polyclonal Lapin est utilisé pour la détection de CCR5 dans des échantillons de Humain et Souris. Il a été validé pour WB.

Aperçu rapide pour CCR5 anticorps (Middle Region) (ABIN927305)

Antigène: CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCR5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CCR5 anticorps

Épitope: Middle Region

Réactivité croisée: Souris

Purification: Purified

Immunogène: CCR5 antibody was raised in rabbit using the middle region of CCR5 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

CCR5 Blocking Peptide, (ABIN5612739), is also available for use as a blocking control in assays to test for specificity of this CCR5 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur CCR5

Antigène: CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

Autre désignation: CCR5

Sujet: CCR5 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this protein was also detected in a promyeloblastic cell line, suggesting that CCR5 may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Synonyms: Polyclonal CCR5 antibody, Anti-CCR5 antibody, chemokine, C-C motif receptor 5 antibody, CC-CKR-5 antibody, CCCKR5 antibody, CD195 antibody, CKR-5 antibody, CKR5 antibody, CMKBR5 antibody.

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size