Estrogen Receptor alpha anticorps (C-Term)

N° du produit ABIN927316

Cet anticorps Lapin Polyclonal détecte spécifiquement Estrogen Receptor alpha dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour Estrogen Receptor alpha anticorps (C-Term) (ABIN927316)

Antigène: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Estrogen Receptor alpha est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Estrogen Receptor alpha anticorps

Épitope: C-Term

Purification: Purified

Immunogène: ESR1 antibody was raised in rabbit using the C terminal of ESR1 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

ESR1 Blocking Peptide, (ABIN940517), is also available for use as a blocking control in assays to test for specificity of this ESR1 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur Estrogen Receptor alpha

Antigène: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Autre désignation: ESR1

Sujet: ESR1 is an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. Synonyms: Polyclonal ESR1 antibody, Anti-ESR1 antibody, estrogen receptor 1 antibody, DKFZp686N23123 antibody, ER antibody, ESR antibody, ESRA antibody, Era antibody, NR3A1 antibody.

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly