PHD1 anticorps (N-Term)

N° du produit ABIN927491

L’anticorps Lapin Polyclonal anti-PHD1 a été validé pour WB. Il convient pour détecter PHD1 dans des échantillons de Humain, Souris, Rat et Chien.

Aperçu rapide pour PHD1 anticorps (N-Term) (ABIN927491)

Antigène: PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHD1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PHD1 anticorps

Épitope: N-Term

Réactivité croisée: Souris, Rat (Rattus), Chien

Purification: Purified

Immunogène: EGLN2 antibody was raised in rabbit using the N terminal of EGLN2 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

EGLN2 Blocking Peptide, (ABIN5613318), is also available for use as a blocking control in assays to test for specificity of this EGLN2 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur PHD1

Antigène: PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))

Autre désignation: EGLN2

Sujet: The hypoxia inducible factor (HIF) is a transcriptional complex which is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. EGLN2 encodes an enzyme responsible for this posttranslational modification. Alternative splicing of EGLN2 results in three transcript variants encoding different isoforms. Synonyms: Polyclonal EGLN2 antibody, Anti-EGLN2 antibody, egl nine homolog 2, C. elegans antibody.

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Cell RedoxHomeostasis