MAF anticorps (N-Term)

N° du produit ABIN927724

Cet anticorps Lapin Polyclonal détecte spécifiquement MAF dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Poulet et Chien.

Aperçu rapide pour MAF anticorps (N-Term) (ABIN927724)

Antigène: MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Poulet, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAF est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MAF anticorps

Épitope: N-Term

Réactivité croisée: Souris, Rat (Rattus), Boeuf (Vache), Poulet, Chien, Poisson zebré (Brachydanio rerio)

Purification: Purified

Immunogène: MAF antibody was raised in rabbit using the N terminal of MAF as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

MAF Blocking Peptide, (ABIN5614625), is also available for use as a blocking control in assays to test for specificity of this MAF antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur MAF

Antigène: MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))

Autre désignation: MAF

Sujet: MAF acts as a transcriptional activator or repressor. It is involved in embryonic lens fiber cell development. It recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. MAF is also involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. When overexpressed, MAF represses anti-oxidant reponse element (ARE)-mediated transcription. It may be involved either as an oncogene or as a tumor suppressor, depending on the cell context. Synonyms: Polyclonal MAF antibody, Anti-MAF antibody, v-maf musculoaponeurotic fibrosarcoma oncogene homolog, avian antibody, MGC71685 antibody.