RBM5 anticorps (N-Term)

N° du produit ABIN927731

L’anticorps Lapin Polyclonal anti-RBM5 a été validé pour WB. Il convient pour détecter RBM5 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Poulet et Xenopus laevis.

Aperçu rapide pour RBM5 anticorps (N-Term) (ABIN927731)

Antigène: RBM5 (RNA Binding Motif Protein 5 (RBM5))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poulet, Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RBM5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RBM5 anticorps

Épitope: N-Term

Réactivité croisée: Souris, Rat (Rattus), Boeuf (Vache), Chien, Grenouille, Poulet

Purification: Purified

Immunogène: RBM5 antibody was raised in rabbit using the N terminal of RBM5 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

RBM5 Blocking Peptide, (ABIN938939), is also available for use as a blocking control in assays to test for specificity of this RBM5 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur RBM5

Antigène: RBM5 (RNA Binding Motif Protein 5 (RBM5))

Autre désignation: RBM5

Sujet: RBM5 is a component of the spliceosome A complex.It regulates alternative splicing of a number of mRNAs. RBM5 may modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. RBM5 may both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, RBM5 promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis. Synonyms: Polyclonal RBM5 antibody, Anti-RBM5 antibody, RNA binding motif protein 5 antibody, FLJ39876 antibody, G15 antibody, H37 antibody, LUCA15 antibody, RMB5 antibody.

Pathways: Ribonucleoprotein Complex Subunit Organization