Amylin/DAP anticorps (N-Term)

N° du produit ABIN927970

Cet anticorps Lapin Polyclonal détecte spécifiquement Amylin/DAP dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Amylin/DAP anticorps (N-Term) (ABIN927970)

Antigène: Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Amylin/DAP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Amylin/DAP anticorps

Épitope: N-Term

Purification: Purified

Immunogène: IAPP antibody was raised in rabbit using the N terminal of IAPP as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

IAPP Blocking Peptide, (ABIN5614120), is also available for use as a blocking control in assays to test for specificity of this IAPP antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur Amylin/DAP

Antigène: Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))

Autre désignation: IAPP

Sujet: Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. Synonyms: Polyclonal IAPP antibody, Anti-IAPP antibody, islet amyloid polypeptide antibody, AMYLIN antibody, DAP antibody, IAP antibody.

Pathways: Hormone Activity, Feeding Behaviour