PSMC3IP anticorps (C-Term)

N° du produit ABIN928182

Cet anticorps anti-PSMC3IP est un anticorps Lapin Polyclonal détectant PSMC3IP dans WB. Adapté pour Souris, Humain, Rat, Chien, Boeuf (Vache), Poisson zèbre (Danio rerio), Poulet et Xenopus laevis.

Aperçu rapide pour PSMC3IP anticorps (C-Term) (ABIN928182)

Antigène: PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))

Reactivité: Souris, Humain, Rat, Chien, Boeuf (Vache), Poisson zèbre (Danio rerio), Poulet, Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMC3IP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PSMC3IP anticorps

Épitope: C-Term

Réactivité croisée: Souris, Rat (Rattus), Grenouille, Chien, Poulet, Boeuf (Vache), Poisson zebré (Brachydanio rerio)

Purification: Purified

Immunogène: PSMC3 IP antibody was raised in rabbit using the C terminal of PSMC3 P as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

PSMC3IP Blocking Peptide, (ABIN5615629), is also available for use as a blocking control in assays to test for specificity of this PSMC3IP antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur PSMC3IP

Antigène: PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))

Autre désignation: PSMC3IP

Sujet: PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3. Synonyms: Polyclonal PSMC3IP antibody, Anti-PSMC3IP antibody, PSMC3 interacting protein antibody, GT198 antibody, HOP2 antibody, TBPIP antibody.