SIN3B anticorps (Middle Region)

N° du produit ABIN928396

Cet anticorps Lapin Polyclonal détecte spécifiquement SIN3B dans WB. Il présente une réactivité envers Humain, Souris, Boeuf (Vache), Poisson zèbre (Danio rerio) et Xenopus laevis.

Aperçu rapide pour SIN3B anticorps (Middle Region) (ABIN928396)

Antigène: SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))

Reactivité: Humain, Souris, Boeuf (Vache), Poisson zèbre (Danio rerio), Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIN3B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SIN3B anticorps

Épitope: Middle Region

Réactivité croisée: Souris, Boeuf (Vache), Grenouille, Poisson zebré (Brachydanio rerio)

Purification: Purified

Immunogène: SIN3 B antibody was raised in rabbit using the middle region of SIN3 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

SIN3B Blocking Peptide, (ABIN5616150), is also available for use as a blocking control in assays to test for specificity of this SIN3B antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur SIN3B

Antigène: SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))

Autre désignation: SIN3B

Sujet: SIN3B acts as a transcriptional repressor. It interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also, it interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. The gene is also able to form a complex with FOXK1 which represses transcription. Synonyms: Polyclonal SIN3B antibody, Anti-SIN3B antibody, SIN3 homolog B, transcription regulator, yeast antibody, KIAA0700 antibody.