GAD anticorps (N-Term)

N° du produit ABIN928718

L’anticorps Lapin Polyclonal anti-GAD a été validé pour WB et IHC. Il convient pour détecter GAD dans des échantillons de Humain et Souris.

Aperçu rapide pour GAD anticorps (N-Term) (ABIN928718)

Antigène: GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GAD est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-GAD anticorps

Épitope: N-Term

Réactivité croisée: Souris

Purification: Purified

Immunogène: Gad1 antibody was raised in rabbit using the N terminal of Gad1 as the immunogen

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Commentaires:

Gad1 Blocking Peptide, (ABIN5613700), is also available for use as a blocking control in assays to test for specificity of this Gad1 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur GAD

Antigène: GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))

Autre désignation: Gad1

Sujet: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in  insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with  seizures. Synonyms: Polyclonal Gad1 antibody, Anti-Gad1 antibody, glutamic acid decarboxylase 1 antibody.