GRM7 anticorps (C-Term)

N° du produit ABIN929284

Cet anticorps Lapin Polyclonal détecte spécifiquement GRM7 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour GRM7 anticorps (C-Term) (ABIN929284)

Antigène: GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRM7 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GRM7 anticorps

Épitope: C-Term

Purification: Purified

Immunogène: GRM7 antibody was raised in rabbit using the C terminal of GRM7 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

GRM7 Blocking Peptide, (ABIN939194), is also available for use as a blocking control in assays to test for specificity of this GRM7 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur GRM7

Antigène: GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))

Autre désignation: GRM7

Sujet: L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. Synonyms: Polyclonal GRM7 antibody, Anti-GRM7 antibody, glutamate receptor, metabotropic 7 antibody, FLJ40498 antibody, GLUR7 antibody, GPRC1G antibody, MGLU7 antibody, MGLUR7 antibody.

Pathways: Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour