GCH1 anticorps (C-Term)

N° du produit ABIN929286

Cet anticorps anti-GCH1 est un anticorps Lapin Polyclonal détectant GCH1 dans WB. Adapté pour Humain.

Aperçu rapide pour GCH1 anticorps (C-Term) (ABIN929286)

Antigène: GCH1 (GTP Cyclohydrolase 1 (GCH1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GCH1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GCH1 anticorps

Épitope: C-Term

Purification: Purified

Immunogène: GCH1 antibody was raised in rabbit using the C terminal of GCH1 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

GCH1 Blocking Peptide, (ABIN5613736), is also available for use as a blocking control in assays to test for specificity of this GCH1 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur GCH1

Antigène: GCH1 (GTP Cyclohydrolase 1 (GCH1))

Autre désignation: GCH1

Sujet: This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described, however, not all variants give rise to a functional enzyme. Synonyms: Polyclonal GCH1 antibody, Anti-GCH1 antibody, GTP cyclohydrolase 1 antibody, DYT14 antibody, DYT5 antibody, DYT5a antibody, GCH antibody, GTP-CH-1 antibody, GTPCH1 antibody, HPABH4B antibody.