GCH1 anticorps (C-Term)

N° du produit ABIN929286

Détail du produit anti-GCH1 anticorps

Antigène: GCH1 (GTP Cyclohydrolase 1 (GCH1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GCH1 est non-conjugé

Application: Western Blotting (WB)

Purification: Purified

Immunogène: GCH1 antibody was raised in rabbit using the C terminal of GCH1 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

GCH1 Blocking Peptide, catalog no. 33R-5373, is also available for use as a blocking control in assays to test for specificity of this GCH1 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur GCH1

Antigène: GCH1 (GTP Cyclohydrolase 1 (GCH1))

Autre désignation: GCH1 (GCH1 Produits)

Synonymes: anticorps DYT14, anticorps DYT5, anticorps DYT5a, anticorps GCH, anticorps GTP-CH-1, anticorps GTPCH1, anticorps HPABH4B, anticorps GTP-CH, anticorps GTPCH, anticorps Gch, anticorps MGC89622, anticorps gch1a, anticorps wu:fc16b10, anticorps zgc:195269, anticorps GTP cyclohydrolase 1, anticorps GTP cyclohydrolase 1-like, anticorps GCH1, anticorps Gch1, anticorps gch1, anticorps Weevi_1190, anticorps Halhy_0838, anticorps Sinme_1220, anticorps Sphch_1077, anticorps LOC100136794

Sujet: This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described, however, not all variants give rise to a functional enzyme. Synonyms: Polyclonal GCH1 antibody, Anti-GCH1 antibody, GTP cyclohydrolase 1 antibody, DYT14 antibody, DYT5 antibody, DYT5a antibody, GCH antibody, GTP-CH-1 antibody, GTPCH1 antibody, HPABH4B antibody.