MRGPRX2 anticorps (Middle Region)

N° du produit ABIN929387

L’anticorps anti-MRGPRX2 Polyclonal Lapin est utilisé pour la détection de MRGPRX2 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour MRGPRX2 anticorps (Middle Region) (ABIN929387)

Antigène: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MRGPRX2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MRGPRX2 anticorps

Épitope: Middle Region

Purification: Purified

Immunogène: MRGPRX2 antibody was raised in rabbit using the middle region of MRGPRX2 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

MRGPRX2 Blocking Peptide, (ABIN5614836), is also available for use as a blocking control in assays to test for specificity of this MRGPRX2 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur MRGPRX2

Antigène: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Autre désignation: MRGPRX2

Sujet: MRGPRX2 is an orphan receptor. It probably involved in the function of nociceptive neurons. It also may regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca2+ but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled. Synonyms: Polyclonal MRGPRX2 antibody, Anti-MRGPRX2 antibody, MAS-related GPR, member X2 antibody, MRGX2 antibody.