CMA1 anticorps (C-Term)

N° du produit ABIN929416

Cet anticorps Lapin Polyclonal détecte spécifiquement CMA1 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour CMA1 anticorps (C-Term) (ABIN929416)

Antigène: CMA1 (Chymase 1, Mast Cell (CMA1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CMA1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CMA1 anticorps

Épitope: C-Term

Purification: Purified

Immunogène: CMA1 antibody was raised in rabbit using the C terminal of CMA1 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

CMA1 Blocking Peptide, (ABIN938181), is also available for use as a blocking control in assays to test for specificity of this CMA1 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur CMA1

Antigène: CMA1 (Chymase 1, Mast Cell (CMA1))

Autre désignation: CMA1

Sujet: CMA1 is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. Synonyms: Polyclonal CMA1 antibody, Anti-CMA1 antibody, chymase 1, mast cell antibody, CYH antibody, MCT1 antibody, MGC119890 antibody, MGC119891 antibody, chymase antibody.

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis