DMP1 anticorps
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- Antigène Voir toutes DMP1 (DMTF1) Anticorps
- DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp DMP1 est non-conjugé
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Application
- Dot Blot (DB)
- Réactivité croisée
- Humain
- Réactivité croisée (Details)
- Other species not studied.
- Purification
- Protein G affinity chromatography
- Immunogène
- DMTF1 antibody was raised in mouse using recombinant Cyclin D Binding Myb-Like Transcription Factor 1
- Clone
- DMTF5I250
- Isotype
- IgG1
- Top Product
- Discover our top product DMTF1 Anticorps primaire
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- Indications d'application
- Optimal conditions should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- Lot specific
- Buffer
- DMTF1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3).
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
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- Antigène
- DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))
- Autre désignation
- DMTF1 (DMTF1 Produits)
- Synonymes
- anticorps DMP1, anticorps DMTF, anticorps hDMP1, anticorps Dimp, anticorps Dmp1, anticorps DMTF1, anticorps zgc:92448, anticorps cyclin D binding myb like transcription factor 1, anticorps cyclin D binding myb-like transcription factor 1, anticorps DMTF1, anticorps Dmtf1, anticorps dmtf1
- Sujet
- This gene encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 40% of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer. Multiple transcript variants encoding different isoforms have been found for this gene. Synonyms: Monoclonal DMTF1 antibody, Anti-DMTF1 antibody, Cyclin D binding myb-like transcription factor 1 antibody, DMP1 antibody, DMTF antibody, hDMP1 antibody.
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