CARD8 anticorps

N° du produit ABIN930979

Cet anticorps Souris Monoclonal détecte spécifiquement CARD8 dans WB, ICC, IP, FACS et DB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CARD8 anticorps (ABIN930979)

Antigène: CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CARD8 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Flow Cytometry (FACS), Dot Blot (DB)

Clone: 2108C2a

Détail du produit anti-CARD8 anticorps

Réactivité croisée: Humain

Réactivité croisée (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogène: CARD8 antibody was raised in mouse using recombinant Human Caspase Recruitment Domain Family, Member 8 (Card8)

Isotype: IgG1

Information d'application

Indications d'application: WB: 0.2-2 µg/mL, IP: 100-500 µg/sample, FC: 0.5-2 µg/sample, ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: CARD8 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Détails sur CARD8

Antigène: CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))

Autre désignation: CARD8

Sujet: The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene. Synonyms: Monoclonal CARD8 antibody, Anti-CARD8 antibody, Caspase recruitment domain family antibody, DACAR antibody, NDPP1 antibody, TUCAN antibody, CARDINAL antibody, KIAA0955 antibody,MGC57162 antibody, DKFZp779L0366 antibody.

Pathways: Positive Regulation of Endopeptidase Activity