AXUD1 anticorps

N° du produit ABIN931016

L’anticorps Souris Monoclonal anti-AXUD1 a été validé pour DB. Il convient pour détecter AXUD1 dans des échantillons de Humain.

Aperçu rapide pour AXUD1 anticorps (ABIN931016)

Antigène: AXUD1 (CSRNP1) (Cysteine-serine-Rich Nuclear Protein 1 (CSRNP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp AXUD1 est non-conjugé

Application: Dot Blot (DB)

Clone: 2055E3a

Détail du produit anti-AXUD1 anticorps

Réactivité croisée: Humain

Réactivité croisée (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogène: AXUD1 antibody was raised in mouse using recombinant Human Axin1 Up-Regulated 1 (Axud1)

Isotype: IgG1

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: AXUD1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Détails sur AXUD1

Antigène: AXUD1 (CSRNP1) (Cysteine-serine-Rich Nuclear Protein 1 (CSRNP1))

Autre désignation: AXUD1

Sujet: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene. Synonyms: Monoclonal AXUD1 antibody, Anti-AXUD1 antibody, AXIN1 up regulated 1 antibody, URAX1 antibody, TAIP-3 antibody, DKFZp566F164 antibody, FAM130B antibody.

Pathways: Platelet-derived growth Factor Receptor Signaling