CTCF anticorps

N° du produit ABIN931147

Cet anticorps Souris Monoclonal détecte spécifiquement CTCF dans ICC et DB. Il présente une réactivité envers Humain.

Aperçu rapide pour CTCF anticorps (ABIN931147)

Antigène: CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CTCF est non-conjugé

Application: Immunocytochemistry (ICC), Dot Blot (DB)

Clone: 252C3a

Détail du produit anti-CTCF anticorps

Réactivité croisée: Humain

Réactivité croisée (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogène: CTCF antibody was raised in mouse using recombinant Human Ccctc-Binding Factor (Zinc Finger Protein)

Isotype: IgG1

Information d'application

Indications d'application: ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: CTCF antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Détails sur CTCF

Antigène: CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))

Autre désignation: CTCF

Sujet: This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Synonyms: Monoclonal CTCF antibody, Anti-CTCF antibody, CCCTC-binding factor (zinc finger protein) antibody.