ORC6 anticorps

N° du produit ABIN931160

L’anticorps Souris Monoclonal anti-ORC6 a été validé pour DB et ICC. Il convient pour détecter ORC6 dans des échantillons de Humain.

Aperçu rapide pour ORC6 anticorps (ABIN931160)

Antigène: ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ORC6 est non-conjugé

Application: Dot Blot (DB), Immunocytochemistry (ICC)

Clone: 2679C2b

Détail du produit anti-ORC6 anticorps

Réactivité croisée: Humain

Réactivité croisée (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogène: ORC6 L antibody was raised in mouse using recombinant Human Origin Recognition Complex, Subunit 6 Like (Yeast) (Orc6 )

Isotype: IgG1

Information d'application

Indications d'application: ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: ORC6 L antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Détails sur ORC6

Antigène: ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))

Autre désignation: ORC6L

Sujet: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. It has been shown that this protein and and ORC1L are loosely associated with the core complex consisting of ORC2L, -3L, -4L and -5L. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis. Synonyms: Monoclonal ORC6L antibody, Anti-ORC6L antibody, Origin recognition complex subunit 6 antibody, ORC6 antibody.

Pathways: Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA