Chitotriosidase 1 anticorps (AA 22-137)

N° du produit ABIN931480

Détail du produit anti-Chitotriosidase 1 anticorps

Antigène: Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))

Épitope: AA 22-137

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Chitotriosidase 1 est non-conjugé

Application: Western Blotting (WB), ELISA

Immunogène: CHIT1 antibody was raised in Mouse using a purified recombinant fragment of CHIT1(aa22-137) expressed in E. coli as the immunogen.

Clone: 1D9G2-1D9G4-2B4G3

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10,000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Détails sur Chitotriosidase 1

Antigène: Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))

Autre désignation: CHIT1 (CHIT1 Produits)

Synonymes: anticorps CHI3, anticorps CHIT, anticorps CHITD, anticorps CHIT1, anticorps chio, anticorps 2300002L19Rik, anticorps chitinase 1, anticorps chitinase 1 (chitotriosidase), anticorps CHIT1, anticorps chit1, anticorps Chit1

Sujet: CHIT1 is a 50 kDa secreted glycoprotein that belongs to glycohydrolase family # 18. It is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Synonyms: Monoclonal CHIT1 antibody, Anti-CHIT1 antibody, Chitinase 1 antibody, Chitotriosidase antibody, CHIT antibody.