HARS1/Jo-1 anticorps
Aperçu rapide pour HARS1/Jo-1 anticorps (ABIN933100)
Antigène
Voir toutes HARS1/Jo-1 (HARS1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Réactivité croisée
- Humain, Souris, Rat (Rattus)
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Réactivité croisée (Details)
- Other species not studied.
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Purification
- Protein G affinity chromatography
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Immunogène
- HARS antibody was raised in mouse using recombinant Histidyl-Trna Synthetase
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Isotype
- IgG1
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Indications d'application
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WB: 0.2-2 µg/mL, IP: 100-500 µg/sample, FC: 0.5-2 µg/sample, ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator. -
Restrictions
- For Research Use only
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Concentration
- Lot specific
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Buffer
- HARS antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
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- HARS1/Jo-1 (HARS1) (Histidyl-tRNA Synthetase (HARS1))
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Autre désignation
- HARS
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Sujet
- Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Synonyms: Monoclonal HARS antibody, Anti-HARS antibody, Histidyl-tRNA synthetase, FLJ20491 antibody, HRS antibody.
Antigène
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