CTCF anticorps (C-Term)

N° du produit ABIN933980

L’anticorps Rat Monoclonal anti-CTCF a été validé pour WB et IF. Il convient pour détecter CTCF dans des échantillons de Souris.

Aperçu rapide pour CTCF anticorps (C-Term) (ABIN933980)

Antigène: CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CTCF est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: KT70

Détail du produit anti-CTCF anticorps

Épitope: C-Term

Purification: Protein G affinity chromatography

Immunogène: CTCF antibody was raised in Rat using Mouse CTCF-C-terminal fragment as the immunogen.

Isotype: IgG2b

Information d'application

Indications d'application: IF: 1-10 µg/mL, WB: 0.1-1 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: Supplied in PBS containing 0.1 % sodium azide as a preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: -20 °C/-80 °C

Stockage commentaire: Store at 4 °C for up to 1 month. For long term storage, aliquot and store at -20 to -80 °C.

Détails sur CTCF

Antigène: CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))

Autre désignation: CTCF

Sujet: The protein CTCF plays heavily in the role of repressing the insulin-like growth factor 2 gene, by binding to the H-19 imprinting control region (ICR) along with differentially-methylated region-1 (DMR1) and MAR3. Binding of targeting sequence elements by CTCF can block the interaction between enhancers and promoters, therefore limiting the activity of enhancers to certain functional domains. Besides acting as enhancer blocking, CTCF can also act as a chromatin barrier by preventing the spread of heterochromatin structures. Synonyms: Monoclonal CTCF antibody, Anti-CTCF antibody, CTC F antibody, CTC-F antibody, Transcriptional repressor CTCF antibody, 11-zinc finger protein antibody, CCCTC-binding factor antibody.