Cet anticorps anti-Blood Group ABH est un anticorps Souris Monoclonal détectant Blood Group ABH dans IHC (p). Adapté pour Humain. Ce Primary Antibody a été cité dans 2+ publications.
The mouse monoclonal antibody HE-10 agglutinates erythrocytes of group A, and is excellent as a tumour marker in patients of blood group B and 0. It does not agglutinate erythrocytes of group B and 0. Study with specific oligosaccharides showed that the antibody HE-10 reacts with A and H antigens with chain types 3 and 4 and it does not react with A disaccharide, A trisaccharide, A type 1, A type 2, ALeb. The antibody HE-10 does not react with normal tissue sections of donors with blood group B and 0 but it reacts specifically with malignant tissues.
Réactivité croisée (Details)
Human
Purification
Hybridoma culture supernatant concentrated by membrane ultrafiltration.
Immunogène
Mixture of erythrocytes of group A1 and glycoprotein fraction isolated from saliva of secretors with blood group A.
Reactivité: Humain
FACS
Hôte: Souris
Monoclonal
HE-10
PE
Indications d'application
Immunohistochemistry (paraffin sections): The antibody HE-10 is excellent as a tumour marker in patients of blood group B and 0. Flow cytometry: Recommended dilution: 1-3 : 100.
Restrictions
For Research Use only
Format
Liquid
Conseil sur la manipulation
Do not freeze. Avoid prolonged exposure to light.
Stock
4 °C
Stockage commentaire
Store at 2-8°C. Do not freeze.
Vanák, Drímalová, Smyslová, N?mec, Viklický, Wisniewski: "Detection of blood group A antigen expression in human colon cancer using monoclonal antibodies with different specificities." dans: Neoplasma, Vol. 36, Issue 4, pp. 479-88, (1989) (PubMed).
N?mec, Drímalová, Horejsí, Vanák, Bártek, Viklický: "Murine monoclonal antibodies to human A erythrocytes: differential reactivity with N-acetyl-D-galactosamine." dans: Vox sanguinis, Vol. 52, Issue 1-2, pp. 125-8, (1987) (PubMed).