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CD27 anticorps

CD27 Reactivité: Humain FACS Hôte: Souris Monoclonal LT27 unconjugated
N° du produit ABIN94051
  • Antigène Voir toutes CD27 Anticorps
    CD27 (CD27 Molecule (CD27))
    Reactivité
    • 188
    • 61
    • 46
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 104
    • 89
    • 15
    • 11
    • 3
    • 1
    Souris
    Clonalité
    • 133
    • 88
    • 2
    Monoclonal
    Conjugué
    • 73
    • 23
    • 22
    • 14
    • 11
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD27 est non-conjugé
    Application
    • 145
    • 84
    • 51
    • 35
    • 33
    • 20
    • 17
    • 13
    • 13
    • 13
    • 11
    • 7
    • 6
    • 4
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    • 3
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    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
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    • 1
    Flow Cytometry (FACS)
    Specificité
    The antibody LT27 reacts with an extracellular epitope of CD27 (T14), a 50-55 kDa type I transmembrane glycoprotein (member of the TNF-receptor superfamily) expressed on medullary thymocytes, peripheral T lymphocytes, some B lymphocytes and NK cells.
    Réactivité croisée (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography.
    Pureté
    > 95 % (by SDS-PAGE)
    Immunogène
    Human peripheral blood lymphocytes
    Clone
    LT27
    Isotype
    IgG2a
    Top Product
    Discover our top product CD27 Anticorps primaire
  • Indications d'application
    Flow cytometry: Recommended dilution: 2 μg/mL.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Antigène
    CD27 (CD27 Molecule (CD27))
    Autre désignation
    CD27 (CD27 Produits)
    Synonymes
    anticorps TNFRSF7, anticorps S152, anticorps Tnfrsf7, anticorps Tp55, anticorps S152. LPFS2, anticorps T14, anticorps CD27 molecule, anticorps CD27 antigen, anticorps CD27, anticorps Cd27
    Sujet
    CD27 Molecule,CD27 is a transmembrane 55 kDa protein of the nerve growth factor-receptor family, expressed as a disulfide-linked homodimer on mature thymocytes, peripheral blood T cells and a subpopulation of B cells. Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. This sCD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T cells through the protease-activated receptors (PARs), degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70.,T14, TNFRSF7, LPFS2, S152, Tp55
    ID gène
    939
    UniProt
    P26842
    Pathways
    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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