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ICAM1 anticorps

ICAM1 Reactivité: Humain WB, FACS, IHC (p), IHC (fro), ICC Hôte: Souris Monoclonal 1H4 unconjugated
N° du produit ABIN94178
  • Antigène Voir toutes ICAM1 Anticorps
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    Reactivité
    • 220
    • 87
    • 38
    • 7
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    Humain
    Hôte
    • 120
    • 119
    • 32
    • 4
    • 2
    • 1
    • 1
    • 1
    Souris
    Clonalité
    • 158
    • 119
    • 1
    Monoclonal
    Conjugué
    • 125
    • 26
    • 25
    • 21
    • 12
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ICAM1 est non-conjugé
    Application
    • 169
    • 158
    • 64
    • 63
    • 46
    • 40
    • 36
    • 34
    • 31
    • 28
    • 24
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    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Specificité
    The antibody 1H4 recognizes an extracellular epitope of CD54 (ICAM-1), a 85-110 kDa type I transmembrane glycoprotein (receptor for rhinovirus) expressed on activated endothelial cells, T lymphocytes, B lymphocytes, monocytes, macrophages, granulocytes and dendritic cells, the expression of CD54 is upregulated by activation.
    Réactivité croisée (Details)
    Other not tested, Human
    Purification
    Purified by protein-A affinity chromatography.
    Pureté
    > 95 % (by SDS-PAGE)
    Immunogène
    Raji cells and spleen cells fused with NS1 cells
    Clone
    1H4
    Isotype
    IgG2b
    Top Product
    Discover our top product ICAM1 Anticorps primaire
  • Indications d'application
    Immunohistochemistry (frozen sections): Recommended dilution: 5-10 μg/mL.
    Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/mL, prolonged fixation in buffered formalin can destroy the epitope. High temperature antigen unmasking technique is required.
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4
    Agent conservateur
    Azide free
    Conseil sur la manipulation
    Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Antigène
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    Autre désignation
    CD54 (ICAM1 Produits)
    Synonymes
    anticorps BB2, anticorps CD54, anticorps P3.58, anticorps Icam-1, anticorps Ly-47, anticorps MALA-2, anticorps ICAM, anticorps ICAM-1, anticorps ICAM1, anticorps intercellular adhesion molecule 1, anticorps intercellular adhesion molecule-1, anticorps ICAM1, anticorps Icam1, anticorps ICAM-1
    Classe de substances
    Viral Protein
    Sujet
    Intercellular adhesion molecule 1,CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.,ICAM-1, BB2, P3.58
    ID gène
    3383
    UniProt
    P05362
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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