C-Peptide anticorps

N° du produit ABIN94267

Détail du produit anti-C-Peptide anticorps

Antigène: C-Peptide

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp C-Peptide est non-conjugé

Application: ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Radioimmunoassay (RIA)

Specificité: The mouse monoclonal antibody C-PEP-01 reacts specifically with C-peptide, a part of the proinsulin molecule. Proinsulin consists of three parts: C-peptide and two long strands of amino acids (alpha and beta chains, later become linked together to form the insulin molecule). No cross-reactivity with insulin or other peptide hormones or proteins was observed.

Réactivité croisée (Details): Human

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

Immunogène: Human C-peptide conjugated to bovine serum albumin.

Clone: C-PEP-01

Isotype: IgG1

Information d'application

Indications d'application: Immunohistochemistry (paraffin sections): Recommended dilution: 2-5 μg/mL, positive control: human pancreas (islets of Langerhans).

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Références pour anticorps anti-C-Peptide (ABIN94267)

Koblas, Zacharovova, Berkova, Girman, Saudek: "An acidic pH and activation of phosphoinositide 3-kinase stimulate differentiation of pancreatic progenitors into insulin-producing cells." dans: Transplantation proceedings, Vol. 42, Issue 6, pp. 2075-80, (2010) (PubMed).

Hilgert, Stolba, Kristofová, Stefanová, Bendlová, Lebl, Horejsí: "A monoclonal antibody applicable for determination of C-peptide of human proinsulin by RIA." dans: Hybridoma, Vol. 10, Issue 3, pp. 379-86, (1991) (PubMed).

Détails sur C-Peptide

Antigène: C-Peptide

Abstract: C-Peptide Produits

Synonymes: anticorps insulin 2, anticorps Ins2

Sujet: From every molecule of proinsulin, one molecule of insulin plus one molecule of C-peptide are produced. C-peptide is released into the blood stream in equal amounts to insulin.,C-peptide of proinsulin