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HLA-DP/DR anticorps

L’anticorps Souris Monoclonal anti-HLA-DP/DR a été validé pour FACS, IP, WB et IHC (p). Il convient pour détecter HLA-DP/DR dans des échantillons de Humain et Porc. Il y a 1 publication disponible.
N° du produit ABIN94346

Aperçu rapide pour HLA-DP/DR anticorps (ABIN94346)

Antigène

HLA-DP/DR (MHC Class II HLA-DP/DR (HLA-DP/DR))

Reactivité

Humain, Porc

Hôte

  • 15
Souris

Clonalité

  • 15
Monoclonal

Conjugué

  • 4
  • 4
  • 3
  • 2
  • 2
Cet anticorp HLA-DP/DR est non-conjugé

Application

  • 15
  • 7
  • 7
  • 4
  • 3
Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

HL-38
  • Fonction

    Anti-HLA-DR/DP Purified

    Specificité

    The antibody HL-38 recognizes an extracellular common epitope on beta-chain of human HLA-DR and HLA-DP. DR and DP are the isotypes of human MHC Class II molecules expressed on antigen-presenting cells (APC, dendritic cells, B lymphocytes, monocytes, macrophages).

    Réactivité croisée (Details)

    Human, Porcine

    Purification

    Purified by protein-A affinity chromatography.

    Pureté

    > 95 % (by SDS-PAGE)

    Immunogène

    Raji Burkitt's lymphoma cell line

    Isotype

    IgG2a
  • Indications d'application

    Western blotting: Recommended dilution: 1 μg/mL
    Flow cytometry: Recommended dilution: 1-4 μg/mL

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Do not freeze.

    Stock

    4 °C

    Stockage commentaire

    Store at 2-8°C. Do not freeze.
  • Horejsí, N?mec, Angelisová, Kristofová, Gorga, Hilgert: "Characterization of seven new monoclonal antibodies against human DR, DR + DP and DQ1 + DQ3 antigens." dans: Tissue antigens, Vol. 28, Issue 5, pp. 288-97, (1987) (PubMed).

  • Antigène

    HLA-DP/DR (MHC Class II HLA-DP/DR (HLA-DP/DR))

    Autre désignation

    HLA-DR/DP

    Sujet

    HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system.
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