Cet anticorps anti-HLA-DP/DR est un anticorps Souris Monoclonal détectant HLA-DP/DR dans FACS. Adapté pour Humain et Porc. Ce Primary Antibody a été cité dans 1 publication.
Aperçu rapide pour HLA-DP/DR anticorps (FITC) (ABIN94347)
Antigène
HLA-DP/DR
(MHC Class II HLA-DP/DR (HLA-DP/DR))
Reactivité
Humain, Porc
Hôte
Souris
Clonalité
Monoclonal
Conjugué
Cet anticorp HLA-DP/DR est conjugé à/à la FITC
Application
Flow Cytometry (FACS)
Clone
HL-38
Fonction
Anti-HLA-DR/DP FITC
Specificité
The antibody HL-38 recognizes an extracellular common epitope on beta-chain of human HLA-DR and HLA-DP. DR and DP are the isotypes of human MHC Class II molecules expressed on antigen-presenting cells (APC, dendritic cells, B lymphocytes, monocytes, macrophages).
Réactivité croisée (Details)
Human, Porcine
Purification
Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Do not freeze. Avoid prolonged exposure to light.
Stock
4 °C
Stockage commentaire
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Horejsí, N?mec, Angelisová, Kristofová, Gorga, Hilgert: "Characterization of seven new monoclonal antibodies against human DR, DR + DP and DQ1 + DQ3 antigens." dans: Tissue antigens, Vol. 28, Issue 5, pp. 288-97, (1987) (PubMed).
Antigène
HLA-DP/DR
(MHC Class II HLA-DP/DR (HLA-DP/DR))
Autre désignation
HLA-DR/DP
Sujet
HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system.