IgE anticorps
Aperçu rapide pour IgE anticorps (ABIN94399)
Antigène
Voir toutes IgE AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- Anti-Hu IgE Purified
-
Specificité
- The mouse monoclonal antibody 4H10 reacts with human IgE, it recognizes an epitope different from the ones recognized by BE5 and 4G7.325 antibodies to IgE. The epitope is located within the amino acids 267-279 (TWLEDGQVMDVDL).
-
Réactivité croisée (Details)
- Human
-
Purification
- Purified by protein-A affinity chromatography.
-
Pureté
- > 95 % (by SDS-PAGE)
-
Immunogène
- Purified human IgE.
-
Isotype
- IgG1
-
-
-
-
Indications d'application
- Flow cytometry: Recommended dilution: 4 μg/mL.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Do not freeze.
-
Stock
- 4 °C
-
Stockage commentaire
- Store at 2-8°C. Do not freeze.
-
-
- IgE
-
Sujet
- Immunoglobulin E (IgE) is a 180 kDa soluble protein serving as an antigen-specific unit of mast cell effector mechanisms. IgE has the lowest serum concentration of all immunoglobulins (approximately 0.5 mg/l) in healthy individuals, but upon allergen challenge its concentration in blood increases dramatically. Although biological survival of free IgE is very short (T1/2 = 2 days), it is stabilized after binding to its high affinity receptor. Unlike IgM- IgG- and IgA-committed B cells, IgE-switched B cells do not undergo clonal expansion.,Immunoglobulin E
-
Poids moléculaire
- 180 kDa
Antigène
-