Actin-Like 7A anticorps (N-Term)
Aperçu rapide pour Actin-Like 7A anticorps (N-Term) (ABIN950263)
Antigène
Voir toutes Actin-Like 7A (ACTL7A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 48-75, N-Term
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Specificité
- This antibody reacts to ACTL7A.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Affinity chromatography on Protein A
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Immunogène
- KLH conjugated synthetic peptide between 48-75 amino acids from the N-terminal region of human ACTL7A
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) sodium azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Actin-Like 7A (ACTL7A)
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Autre désignation
- ACTL7A
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Sujet
- ACTL7A is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. ACTL7A (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known.Synonyms: Actin-like protein 7A, Actin-like-7-alpha
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ID gène
- 10881
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NCBI Accession
- NP_006678
Antigène
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