ALX4 anticorps (Middle Region)
Aperçu rapide pour ALX4 anticorps (Middle Region) (ABIN950384)
Antigène
Voir toutes ALX4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 256-283, Middle Region
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Specificité
- This antibody reacts to ALX4.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Affinity chromatography on Protein A
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Immunogène
- KLH conjugated synthetic peptide between 256-283 amino acids from the Central region of human ALX4
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) sodium azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ALX4 (ALX Homeobox 4 (ALX4))
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Autre désignation
- ALX4
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Sujet
- This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2), an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism, suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS), a syndrome characterized by craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart.Synonyms: Homeobox protein aristaless-like 4, KIAA1788
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ID gène
- 60529
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NCBI Accession
- NP_068745
Antigène
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