ANGPTL4 anticorps (Middle Region)
Aperçu rapide pour ANGPTL4 anticorps (Middle Region) (ABIN950414)
Antigène
Voir toutes ANGPTL4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 145-175, Middle Region
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Specificité
- This antibody reacts to ANGPTL4.
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Réactivité croisée (Details)
- Species reactivity (tested):Human and Mouse.
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Purification
- Saturated Ammonium Sulfate (SAS) precipitation
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Immunogène
- KLH conjugated synthetic peptide between 145~175 amino acids from the Center region of human ANGPTL4
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) sodium azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))
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Autre désignation
- ANGPTL4 / FIAF
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Sujet
- ANGPTL4 is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This protein is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes.Synonyms: ARP4, Angiopoietin-like 4, Angiopoietin-related protein 4, Fasting-induced adipose factor, HFARP, Hepatic fibrinogen/angiopoietin-related protein, PGAR
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ID gène
- 51129
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NCBI Accession
- NP_001034756
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Pathways
- Regulation of Lipid Metabolism by PPARalpha
Antigène
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