ANAPC5 anticorps (Middle Region)

N° du produit ABIN950454

Cet anticorps anti-ANAPC5 Polyclonal Lapin (ABIN950454) détecte spécifiquement ANAPC5 dans WB et EIA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ANAPC5 anticorps (Middle Region) (ABIN950454)

Antigène: ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANAPC5 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-ANAPC5 anticorps

Épitope: AA 156-185, Middle Region

Specificité: This antibody reacts to APC5.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 156-185 amino acids from the Central region of human ANAPC5

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ANAPC5

Antigène: ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

Autre désignation: APC5 / ANAPC5

Sujet: This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.Synonyms: Anaphase-promoting complex subunit 5, Cyclosome subunit 5

ID gène: 51433

NCBI Accession: NP_057321

Pathways: M Phase