CHN2 anticorps (Middle Region)

N° du produit ABIN950491

Détail du produit anti-CHN2 anticorps

Antigène: CHN2 (Chimerin (Chimaerin) 2 (CHN2))

Épitope: AA 162-192, Middle Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHN2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects ARHGAP3/CHN2.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse

Purification: Purified through a protein A column; followed by peptide affinity purification.

Immunogène: Synthetic peptide - KLH conjugated - corresponding to the central region ( between 162-192aa) of human CHN2.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CHN2

Antigène: CHN2 (Chimerin (Chimaerin) 2 (CHN2))

Autre désignation: ARHGAP3 / CHN2 (CHN2 Produits)

Synonymes: anticorps 1700026N20Rik, anticorps 4930557O16Rik, anticorps ARHGAP3, anticorps Bch, anticorps BCH, anticorps CHN2-3, anticorps RHOGAP3, anticorps chimerin 2, anticorps chimerin 2 L homeolog, anticorps chn2, anticorps CHN2, anticorps Chn2, anticorps chn2.L

Sujet: The CHN2 gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Synonyms: BCH, Beta-chimaerin, Beta-chimerin, Rho GTPase-activating protein 3

ID gène: 1124

NCBI Accession: NP_001035025