Asialoglycoprotein Receptor 1 anticorps (N-Term)

N° du produit ABIN950533

Cet anticorps Lapin Polyclonal détecte spécifiquement Asialoglycoprotein Receptor 1 dans WB et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour Asialoglycoprotein Receptor 1 anticorps (N-Term) (ABIN950533)

Antigène: Asialoglycoprotein Receptor 1 (ASGR1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Asialoglycoprotein Receptor 1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-Asialoglycoprotein Receptor 1 anticorps

Épitope: AA 1-30, N-Term

Specificité: This antibody reacts to ASGR1.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ASGR1

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Asialoglycoprotein Receptor 1

Antigène: Asialoglycoprotein Receptor 1 (ASGR1)

Autre désignation: ASGR1

Sujet: Partially deglycosylated plasma glycoproteins and immunoglobulin IgA2 allotypes are efficiently and specifically removed from circulation by a receptor-mediated process. The asialoglycoprotein receptor binds to desialylated (galactosyl-terminal) glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociate. Then the receptor is recycled back to the cell surface and the ligand is transported to the lysosomes for degradation. Alternatively spliced transcript variants encoding distinct isoforms have been identified.Synonyms: ASGP-R 1, ASGPR 1, Asialoglycoprotein receptor 1, Hepatic lectin H1

ID gène: 432

NCBI Accession: NP_001184145

Pathways: Thyroid Hormone Synthesis