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ASXL1 anticorps (AA 521-549)

ASXL1 Reactivité: Humain, Souris WB, FACS, IF, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN950543
  • Antigène Voir toutes ASXL1 Anticorps
    ASXL1 (Additional Sex Combs Like 1 (ASXL1))
    Épitope
    • 8
    • 6
    • 6
    • 6
    • 3
    • 2
    • 1
    AA 521-549
    Reactivité
    • 27
    • 24
    • 1
    Humain, Souris
    Hôte
    • 29
    • 2
    Lapin
    Clonalité
    • 29
    • 2
    Polyclonal
    Conjugué
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ASXL1 est non-conjugé
    Application
    • 22
    • 16
    • 14
    • 13
    • 13
    • 5
    • 3
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects ASXL1 at Center.
    Réactivité croisée (Details)
    Species reactivity (tested):Mouse.
    Purification
    Affinity Chromatography on Protein A
    Immunogène
    KLH conjugated synthetic peptide between 521-549 amino acids from the Central region of human ASXL.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ASXL1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS, 0.09 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    ASXL1 (Additional Sex Combs Like 1 (ASXL1))
    Autre désignation
    ASXL1 (ASXL1 Produits)
    Synonymes
    anticorps asxl1, anticorps MGC83850, anticorps mKIAA0978, anticorps BOPS, anticorps MDS, anticorps additional sex combs like 1, transcriptional regulator L homeolog, anticorps additional sex combs like 1, transcriptional regulator, anticorps additional sex combs like 1, anticorps asxl1.L, anticorps ASXL1, anticorps asxl1, anticorps Asxl1
    Sujet
    This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants.Synonyms: Additional sex combs-like protein 1, KIAA0978, Putative Polycomb group protein ASXL1
    Poids moléculaire
    165432 Da
    ID gène
    171023
    NCBI Accession
    NP_056153
    Pathways
    Retinoic Acid Receptor Signaling Pathway
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