CRYGS anticorps (C-Term)

N° du produit ABIN950652

Cet anticorps anti-CRYGS Polyclonal Lapin (ABIN950652) détecte spécifiquement CRYGS dans WB et EIA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour CRYGS anticorps (C-Term) (ABIN950652)

Antigène: CRYGS (Crystallin, gamma S (CRYGS))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRYGS est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-CRYGS anticorps

Épitope: AA 136-166, C-Term

Specificité: This antibody reacts to human and mouse CRYGS.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 136-166 amino acids from the C-terminal region of human CRYGS

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CRYGS

Antigène: CRYGS (Crystallin, gamma S (CRYGS))

Autre désignation: beta-Crystallin S

Sujet: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. This gene encodes a protein initially considered to be a beta-crystallin but the encoded protein is monomeric and has greater sequence similarity to other gamma-crystallins. This gene encodes the most significant gamma-crystallin in adult eye lens tissue. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.Synonyms: CRYGS, GRYG8, Gamma-S-crystallin, Gamma-crystallin S

Poids moléculaire: 21007 Da

ID gène: 1427

NCBI Accession: NP_060011