BHLHA15 anticorps (C-Term)

N° du produit ABIN950660

Détail du produit anti-BHLHA15 anticorps

Antigène: BHLHA15 (Basic Helix-Loop-Helix Family, Member A15 (BHLHA15))

Épitope: AA 167-197, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BHLHA15 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to BHLHB8.

Réactivité croisée (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 167-197 amino acids from the C-terminal region of human BHLHA15

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur BHLHA15

Antigène: BHLHA15 (Basic Helix-Loop-Helix Family, Member A15 (BHLHA15))

Autre désignation: BHLHB8 / BHLHA15 (BHLHA15 Produits)

Synonymes: anticorps BHLHB8, anticorps MIST1, anticorps 1810009C13Rik, anticorps Bhlhb8, anticorps MIST-1, anticorps Mist1, anticorps bHlH, anticorps basic helix-loop-helix family member a15, anticorps basic helix-loop-helix family, member a15, anticorps BHLHA15, anticorps Bhlha15

Sujet: Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3' (By similarity).Synonyms: Class A basic helix-loop-helix protein 15, Class B basic helix-loop-helix protein 8, MIST1, Muscle, intestine and stomach expression 1

ID gène: 168620

NCBI Accession: NP_803238